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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXO21 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23014
Official gene symbolFBXO21
Full nameF-box protein 21
Aliases,DKFZp434G058,FBX21,FLJ90233,KIAA0875,MGC26682,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.22
Gene position117628300 - 117581585  Map Viewer
Gene orientationminus
Gene size46716 bp
Gene sequence
OMIM ID609095