Entrez gene ID | | 23081 |
Official gene symbol | | KDM4C |
Full name | | lysine (K)-specific demethylase 4C |
Aliases | | ,FLJ25949,GASC1,JHDM3C,JMJD2C,KIAA0780,bA146B14.1, |
Gene summary | | This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9p24.1 |
Gene position | | 6720863 - 7175648 Map Viewer |
Gene orientation | | plus |
Gene size | | 454786 bp |
Gene sequence |
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OMIM ID | | 605469 |
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