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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PEG10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23089
Official gene symbolPEG10
Full namepaternally expressed 10
Aliases,EDR,HB-1,KIAA1051,MEF3L,Mar2,Mart2,RGAG3,
Gene summaryThis is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q21
Gene position94285637 - 94299007  Map Viewer
Gene orientationplus
Gene size13371 bp
Gene sequence
OMIM ID609810