Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAPK8IP3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23162
Official gene symbolMAPK8IP3
Full namemitogen-activated protein kinase 8 interacting protein 3
Aliases,DKFZp762N1113,FLJ00027,JIP3,JSAP1,KIAA1066,SYD2,syd,
Gene summaryThe protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]
LocationChromosome: 16   Locus: 16p13.3
Gene position1756221 - 1820318  Map Viewer
Gene orientationplus
Gene size64098 bp
Gene sequence
OMIM ID605431