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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ATG4B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23192
Official gene symbolATG4B
Full nameATG4 autophagy related 4 homolog B (S. cerevisiae)
Aliases,APG4B,AUTL1,MGC1353,
Gene summaryAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q37.3
Gene position242577027 - 242613272  Map Viewer
Gene orientationplus
Gene size36246 bp
Gene sequence
OMIM ID611338