Entrez gene ID | | 23192 |
Official gene symbol | | ATG4B |
Full name | | ATG4 autophagy related 4 homolog B (S. cerevisiae) |
Aliases | | ,APG4B,AUTL1,MGC1353, |
Gene summary | | Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q37.3 |
Gene position | | 242577027 - 242613272 Map Viewer |
Gene orientation | | plus |
Gene size | | 36246 bp |
Gene sequence |
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OMIM ID | | 611338 |
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