Entrez gene ID | | 23266 |
Official gene symbol | | LPHN2 |
Full name | | latrophilin 2 |
Aliases | | ,CIRL2,CL2,LEC1,LPHH1, |
Gene summary | | This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p31.1 |
Gene position | | 82266082 - 82458107 Map Viewer |
Gene orientation | | plus |
Gene size | | 192026 bp |
Gene sequence |
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OMIM ID | | 607018 |
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