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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LPHN2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23266
Official gene symbolLPHN2
Full namelatrophilin 2
Aliases,CIRL2,CL2,LEC1,LPHH1,
Gene summaryThis gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. While several transcript variants have been described, the biological validity of only one has been determined. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p31.1
Gene position82266082 - 82458107  Map Viewer
Gene orientationplus
Gene size192026 bp
Gene sequence
OMIM ID607018