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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXW11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23291
Official gene symbolFBXW11
Full nameF-box and WD repeat domain containing 11
Aliases,BTRC2,BTRCP2,FBW1B,FBXW1B,Fbw11,Hos,KIAA0696,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq]
LocationChromosome: 5   Locus: 5q35.1
Gene position171433877 - 171288556  Map Viewer
Gene orientationminus
Gene size145322 bp
Gene sequence
OMIM ID605651