Entrez gene ID | | 23335 |
Official gene symbol | | WDR7 |
Full name | | WD repeat domain 7 |
Aliases | | ,KIAA0541,TRAG, |
Gene summary | | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 18 Locus: 18q21.1-q22 |
Gene position | | 54318616 - 54697036 Map Viewer |
Gene orientation | | plus |
Gene size | | 378421 bp |
Gene sequence |
| |
OMIM ID | | 613473 |
|