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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AFF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2334
Official gene symbolAFF2
Full nameAF4/FMR2 family, member 2
Aliases,FMR2,FRAXE,MRX2,OX19,
Gene summaryThis gene encodes a putative transcriptional activator that is a member of the AF4FMR2 gene family. This gene is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
LocationChromosome: X   Locus: Xq28
Gene position147582139 - 148082193  Map Viewer
Gene orientationplus
Gene size500055 bp
Gene sequence
OMIM ID300806