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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARHGEF12 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23365
Official gene symbolARHGEF12
Full nameRho guanine nucleotide exchange factor (GEF) 12
Aliases,DKFZp686O2372,KIAA0382,LARG,PRO2792,
Gene summaryRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q23.3
Gene position120207946 - 120360645  Map Viewer
Gene orientationplus
Gene size152700 bp
Gene sequence
OMIM ID604763