Entrez gene ID | | 23368 |
Official gene symbol | | PPP1R13B |
Full name | | protein phosphatase 1, regulatory (inhibitor) subunit 13B |
Aliases | | ,ASPP1,KIAA0771,p53BP2-like,p85, |
Gene summary | | This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq] |
Location | | Chromosome: 14 Locus: 14q32.33 |
Gene position | | 104313927 - 104200088 Map Viewer |
Gene orientation | | minus |
Gene size | | 113840 bp |
Gene sequence |
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OMIM ID | | 606455 |