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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ARHGEF18 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23370
Official gene symbolARHGEF18
Full nameRho/Rac guanine nucleotide exchange factor (GEF) 18
Aliases,KIAA0521,MGC15913,P114-RhoGEF,
Gene summaryRho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.3
Gene position7459999 - 7537371  Map Viewer
Gene orientationplus
Gene size77373 bp
Gene sequence