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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SIRT5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23408
Official gene symbolSIRT5
Full namesirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
Aliases,FLJ36950,SIR2L5,
Gene summaryThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p23
Gene position13574792 - 13614790  Map Viewer
Gene orientationplus
Gene size39999 bp
Gene sequence
OMIM ID604483