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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CES3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23491
Official gene symbolCES3
Full namecarboxylesterase 3
Aliases,ES31,FLJ21736,
Gene summaryThis gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.
LocationChromosome: 16   Locus: 16q22.1
Gene position66995132 - 67009052  Map Viewer
Gene orientationplus
Gene size13921 bp
Gene sequence
OMIM ID605279