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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MACF1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23499
Official gene symbolMACF1
Full namemicrotubule-actin crosslinking factor 1
Aliases,ABP620,ACF7,FLJ45612,FLJ46776,KIAA0465,KIAA1251,MACF,OFC4,
Gene summaryThe protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p32-p31
Gene position39547118 - 39952789  Map Viewer
Gene orientationplus
Gene size405672 bp
Gene sequence
OMIM ID608271