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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FOLR2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2350 Official gene symbol FOLR2 Full name folate receptor 2 (fetal) Aliases ,BETA-HFR,FBP/PL-1,FR-BETA,FR-P3, Gene summary The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq] Location Chromosome: 11   Locus: 11q13.3-q13.5 Gene position 71927819 - 71932994  Map Viewer Gene orientation plus Gene size 5176 bp Gene sequence >FOLR2:17233614..17238789:Length=5176 ATTTCACTCAGTGCTTACCAGAGCGCGTTGTCTACCCTGTACCGAAGACAGAGGCTGTGG GGACAGCCTAGGGGCCTGGATCTATTGCCTACTTAGAGAGAGGCCAACTCAGACACAGCC GTGTATGCTCCCAGCAGCAACGGAGGTTCAGGCAAGATGCCCGAAGGAGGGAAGGGTGAC AAGGGCAGTGGGGAGACTTGGAGAGTTTGTGCAGAGGGGAGGAACACACCTTTCTTTCTG TATTGTATTGTATTGTATTGTATTTTTTGAGACAGAGTCTCGCTCTGTCACCCAGGCTGG AGTGCAGTGGCACGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTC CTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGCCCACCACCTCGCCTGGCTAATTT TTGTATTTTTAGTAGAGACGGGGTTTCATCATGTTGGTCAGGCTGGTCTCGAACTCTTGA CCTCAGGATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGT GCCCGGCCACATCTTTCTTTAGAAAGATCATGCTGGCTCCTGTGGGGAAGGCAACTTGAA GGGGAAGAAATTGGAAGAGGGAAGACTTGACACTAAACATAGAGCCATGGTCAGTAAGTT TTTGGAGGGACCTTTACCAGAGAGGGAGAGGAAGCAGTATCCATTATCCACTCTTTAGTG ACAGAGCCCAAAGGAACAGCTCTGTAATGGCTGGGGGTGGGGGCAAGGGCAGCAATGAAC AGAGGAGGCGAGGGCTGCTCCTGTTGTTGAGTGCCTTCCAGGACACTAAGTGCTGGTCTG GCTGCTCCAACATGGGAAACTTTCATGTTGTCTCTCAGATCTAAGGGTCTCTCTGCATTT TTAAAAAAATTATTTTGAATTTTTTAAACTTCTATCGTTTTTCAGGTGGTTTTGGTTGCA TAGATAAGTTCTTTAGTGGTGATTTCTGAATTTTAGTGCACCAGTCACCGGAGCAGTGTA CACTGTACTCAGTATATAGTCTTTTATTCCTCACCCCCTCCTCACCTTGCCCCACCCCCA GTCTATATCATTCTCATCTGCATTTGTTTTTTGAGAGGTAGGGTGAGGTCTGCTGCATTA GCCCAGAGACAGCTGAGGAGGCTGGAAAGGAAAATGGCTTTCAGAGAATAGGGAAGGAAA AAGTCTGAGGAAGCAAAACTACTTAAAAAACACTGCTCTTTCCATTTCCGTATCATTTAA CCAAACACCATCCTGTGGGTTCTGTCACTTGATCCTCATGCTGATCTGAGAACTCGGCAG AGCTGGGTCACTGCCTTCCCCAAGGCTAACCTGGTTTCTAAGCTGGCACAAGACCCCAGG TGATCTATCATCTAACCACAGAGCCCTTGCTGGACAGAGGGTGAAGACATTATGTGTCCC TGGCTCTGTTCAGGGAAGCAGAGGATAGACCTGAAGAATTTAATTACTTGTCATAGATAA AGCCTAGAGAAAAGGTGAGGGCGCAAAGTATCTCCTCCAAATTGGGAAGACTCCCCCAGG GCTCACTCACTAACGCCAGTTCTCCTGAGCCTTTAAAGCCTGGGGGTGAGGGAGCCCTCC TGGTCAACCCTCTCTACCCTAGCCTCAGGGAGCTTCAGGGCCCCAGCATTGAAGGAACAG GGTCTGACCTCATTTGCCACCGTAGGGTTGGGGAGACTGAGGCAGGAGGTGAATGGGCTC CCAGCTTGGAGCCCTTTCCCCTCAGGACTTGGTTTCCCTACCCTAGCTCCGCCTGCAGGG ACAGAAAGACATGGTCTGGAAATGGATGCCACTTCTGCTGCTTCTGGTCTGTGTAGCCAC CATGTGCAGTGCCCAGGACAGGACTGATCTCCTCAATGTCTGTATGGATGCCAAGCACCA CAAGACAAAGCCAGGTCCTGAGGACAAGCTGCATGACCAAGTACGGCTGGAGTGTGCCTC TGCTAAGGAGGGGGCTTGTTCTAACAGGGAGGAGAAAGTCAGGATGGTGGGAGAGGGATT GAGGGGTCAGATACCTCCACATCCTGAAGTTTTCCTGTGGGAGAAGATGAAGGTGGAGTA GGAAGAGTGGCTGAGGTGATTTTAGGGGGGCCCTCCCCGGAGGTGGATACCATGTTGACA ATGATATTGAGTCGTCATTCGATGGGCACCTGTCAGTTGTCATGTGTTTTTTGTACAAAA TTTCATATTCCCAGGGGTTCTTGGATGTAGGTAGATGATATTCTCCACATTACACAAGTA AGTGAAAATGAGGCTCACAGAAGCACATGGGCCCACACAGGAGCTGGACATGAATGGCCC CTGTGGAGGGGTAGGAATAGGAGTGGGTTAGGCTCCTCCTTTGGTGGGTGACAGACTAGG GAGTCGCTGGCTTTTCCCACCCTCACTAAGTGCCATTTCCATGGAGTGCCAAGGGAGAAG AGGAGGAGGCCCTTCTGGCTGTAATTTGAGGCACAGGGGCTGGACATTCACACAGTCTAT ATACATGTATGCCAGGGGATTGCAGCCTTATTAGACTCAATGTCTCCCTTTTATGACAGA TTTTTTTTTAGATTCTCTTTTCTATCCTGCAATGAAATTCAAAGAACCTATTTGTATGCA TAATTTTTGCAAATATCAACATAATGCTCTGTAATATAAAGGAGAAACACACAGAAAGTA ACTTGTAATAAAATAATATATATTTCAATATGTCAGTTCTCTGGTATGACTACATTAGAA GGCATTAGGAAATAGCACATGCTTGCTTTTGTCATAAAATCATTATAAGTGGGGAGCTAC AAATGAAGATTGATACAGGTATATTCTATTGGTGACTTAAACACTATAAGATACTATAAT ATAAGCAATGTTGCTGTTGATGTCATACTTTTCTAAAATAGTGAATAATTCTAGTAGAAT AAACCACATAGTACAGCCTTCTATTTCATGGTATTTGCAGTCCTGGAAAACCCAGTCTAG ATTAAAATCTTGTGAAAACATGATGTGCCTATATGTAAGATAGAGATACATTTAAAAAGT AGGGCTTTTGCTTACTTTTTTTTTTTTTTTTGAGAAGGAGTCTCACTCTGTTGCCCAGGC TGGAGTGCAATGGTGTGATCTCAGCTCACGGCAACCTCCGCCTCCGGGGTTCTGGTGATT CTCCTGCCTCAGCCTCCCAAGTAGCTGGGGCACCCGCCACCATGCCTGGCTAATTTTTTT GTATTTTTACCAGAGACGAGGTTTCACCATGTTGGCCAGGGTGGTCTCAAACTCCTGACC TCAGGTGGTAGACCTGCCTCGGCCTCCCAAAGTGCTGGGGTTACAGCTACGAGCCACCAC GCCCAGCCTGGCTTTTGCTTACTTTTTCCAGCAAATATTTTCATGGGCCTACTATGTGTC TGGCACTGGCCTAGCCACTGGGGACACAGATCTTACTACATGCCAAGAAGAATAAATATA TTCAAACTCCATTACTCCATGGCTCGCTCCCTCTCTTCCTTTGCTCAAAATGTCACCAAT GTGGCATTTCCTAACCTATTTAAAATTTCAGCAATTCCACATTACCATTTCCTGCTCATA TCATTTAACTTTTCCCATATCATTTATCATATCCTGACATACCATATATATATATTTTTT AAGTTTCTTACTGTCTGTCTCCTCTGACCAGAATGAAAATTCCATGAATACATATTTCTG TCTGTTTTGTTCTCTTCTGTATTCCCAGCATCTATAACCGTGACTGGCATAAAGTAGGTG CTCAATAATTTTTAAATGAGTAAGTGAAAGGACTTTTTATGAAGTGTTACATACCTCATA AATGATAACTATTATTCCCAAGACAGGGTTTCCCCTGGGCTCCCACAGTCCCCTGATCAC ACGGTTGTAATTGTGTTTCCTCCAAGAAAGGGGTTCCTGGAGGCCTAGGAGAGAGGGACC ATCATCTGGGAACCTGAGTGTTCTCAGGACAACCTGCCTAGGGCAGAGGAGTAAGAACCA AATGGGGGAGAGACACGAGGTGGCAGGAGGAGGAGGGTATGGGGAGGCACTTAGTCCTGT GTCTTCCCCACCCAGTGCAGTCCCTGGAAGAAGAATGCCTGCTGCACAGCCAGCACCAGC CAGGAGCTGCACAAGGACACCTCCCGCCTGTACAACTTTAACTGGGACCACTGCGGCAAG ATGGAGCCCGCCTGCAAGCGCCACTTCATCCAGGACACCTGTCTCTATGAGTGCTCACCC AACCTGGGGCCCTGGATCCAGCAGGTAGGGTGTCTCCCCCCGACCCACCCCAGCAGACTG CCATCCCCCTCAGTCACTTCAAGGCGATGGCTGCCAGCATCCCTGGCTGAGAGGAGCCCT GCCTCCCCACCTCCCACCCAGGTGAATCAGAGCTGGCGCAAAGAACGCTTCCTGGATGTG CCCTTATGCAAAGAGGACTGTCAGCGCTGGTGGGAGGATTGTCACACCTCCCACACGTGC AAGAGCAACTGGCACAGAGGATGGGACTGGACCTCAGGTGAGGGTGATTGAGTTGGGGTT AGGAAAAAGGAGATTGAGGTAGGGTTTGGAAAATCTTCAAGGATTTGGGGTGGGGTGAAG ATTTCTGGGGGTGGCCAGAAATGAGCTTTGGGCCCAGGGGCTGAAAGTCTGTGTCCACCA TGCCTCTCCCTGCAGGAGTTAACAAGTGCCCAGCTGGGGCTCTCTGCCGCACCTTTGAGT CCTACTTCCCCACTCCAGCTGCCCTTTGTGAAGGCCTCTGGAGTCACTCATACAAGGTCA GCAACTACAGCCGAGGGAGCGGCCGCTGCATCCAGATGTGGTTTGATTCAGCCCAGGGCA ACCCCAACGAGGAAGTGGCGAGGTTCTATGCTGCAGCCATGCATGTGAATGCTGGTGAGA TGCTTCATGGGACTGGGGGTCTCCTGCTCAGTCTGGCCCTGATGCTGCAACTCTGGCTCC TTGGCTGAGTTCAGTCCTCCCAGACTACCTGCCCTCAGCTTGGATAACCAGGCTGGGCTC AGCTCAGCTCCCACAAATGACAGCCCCTTAAGCATGCTTCTATTAGTCACCTAACCCTCT GTCACCCAGTCTGTTGCTGCTCCATGGTGGGGCCAAGAGTCACTTCTAATAAACAGACTG TTTTCTAATAATTCCA OMIM ID 136425