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Gene information for NNT (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23530
Official gene symbolNNT
Full namenicotinamide nucleotide transhydrogenase
Aliases,MGC126502,MGC126503,
Gene summaryThis gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]
LocationChromosome: 5   Locus: 5p13.1-cen
Gene position43602791 - 43705668  Map Viewer
Gene orientationplus
Gene size102878 bp
Gene sequence
OMIM ID607878