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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PRAME (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23532
Official gene symbolPRAME
Full namepreferentially expressed antigen in melanoma
Aliases,CT130,MAPE,OIP4,
Gene summaryThis gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.22
Gene position22901696 - 22890123  Map Viewer
Gene orientationminus
Gene size11574 bp
Gene sequence
OMIM ID606021