Entrez gene ID | | 23542 |
Official gene symbol | | MAPK8IP2 |
Full name | | mitogen-activated protein kinase 8 interacting protein 2 |
Aliases | | ,IB2,JIP2,PRKM8IPL, |
Gene summary | | The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q13.33 |
Gene position | | 51039131 - 51049979 Map Viewer |
Gene orientation | | plus |
Gene size | | 10849 bp |
Gene sequence |
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OMIM ID | | 607755 |
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