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Gene information for FPGS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2356
Official gene symbolFPGS
Full namefolylpolyglutamate synthase
Aliases,-,
Gene summaryThis gene encodes the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives. While several transcript variants may exist for this gene, the full-length natures of only two have been biologically validated to date. These two variants encode distinct isoforms. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q34.1
Gene position130565154 - 130576556  Map Viewer
Gene orientationplus
Gene size11403 bp
Gene sequence