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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LEMD3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23592
Official gene symbolLEMD3
Full nameLEM domain containing 3
Aliases,MAN1,
Gene summaryThis locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.
LocationChromosome: 12   Locus: 12q14
Gene position65563351 - 65642141  Map Viewer
Gene orientationplus
Gene size78791 bp
Gene sequence
OMIM ID607844