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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CD2AP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23607
Official gene symbolCD2AP
Full nameCD2-associated protein
Aliases,CMS,DKFZp586H0519,
Gene summaryThis gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p12
Gene position47445525 - 47594999  Map Viewer
Gene orientationplus
Gene size149475 bp
Gene sequence
OMIM ID604241