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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NTSR2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23620
Official gene symbolNTSR2
Full nameneurotensin receptor 2
Aliases,NTR2,
Gene summaryThe protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p25.1
Gene position11810329 - 11798304  Map Viewer
Gene orientationminus
Gene size12026 bp
Gene sequence
OMIM ID605538