| Entrez gene ID | | 23621 |
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| Official gene symbol | | BACE1 |
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| Full name | | beta-site APP-cleaving enzyme 1 |
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| Aliases | | ,ASP2,BACE,FLJ90568,HSPC104,KIAA1149, |
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| Gene summary | | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
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| Location | | Chromosome: 11 Locus: 11q23.2-q23.3 |
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| Gene position | | 117186972 - 117156414 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 30559 bp |
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| Gene sequence |
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| OMIM ID | | 604252 |
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