Entrez gene ID | | 23626 |
Official gene symbol | | SPO11 |
Full name | | SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae) |
Aliases | | ,CT35,MGC39953, |
Gene summary | | Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.2-q13.3 |
Gene position | | 55904831 - 55919049 Map Viewer |
Gene orientation | | plus |
Gene size | | 14219 bp |
Gene sequence |
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OMIM ID | | 605114 |
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