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Gene information for KPNA6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23633
Official gene symbolKPNA6
Full namekaryopherin alpha 6 (importin alpha 7)
Aliases,FLJ11249,IPOA7,KPNA7,MGC17918,
Gene summaryNucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p35.1-p34.3
Gene position32573644 - 32642169  Map Viewer
Gene orientationplus
Gene size68526 bp
Gene sequence
OMIM ID610563