Entrez gene ID | | 23641 |
Official gene symbol | | LDOC1 |
Full name | | leucine zipper, down-regulated in cancer 1 |
Aliases | | ,BCUR1,Mar7,Mart7, |
Gene summary | | The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq27 |
Gene position | | 140271310 - 140269930 Map Viewer |
Gene orientation | | minus |
Gene size | | 1381 bp |
Gene sequence |
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OMIM ID | | 300402 |
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