Entrez gene ID | | 23761 |
Official gene symbol | | PISD |
Full name | | phosphatidylserine decarboxylase |
Aliases | | ,DJ858B16,DKFZp566G2246,PSD,PSDC,PSSC,dJ858B16.2, |
Gene summary | | Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 [PubMed 19165886]).[supplied by OMIM] |
Location | | Chromosome: 22 Locus: 22q12.2 |
Gene position | | 32026810 - 32014477 Map Viewer |
Gene orientation | | minus |
Gene size | | 12334 bp |
Gene sequence |
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OMIM ID | | 612770 |
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