Entrez gene ID | | 23762 |
Official gene symbol | | OSBP2 |
Full name | | oxysterol binding protein 2 |
Aliases | | ,ORP-4,ORP4,OSBPL1,OSBPL4, |
Gene summary | | Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q12.2 |
Gene position | | 31090793 - 31303811 Map Viewer |
Gene orientation | | plus |
Gene size | | 213019 bp |
Gene sequence |
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OMIM ID | | 606729 |