Entrez gene ID | | 23765 |
Official gene symbol | | IL17RA |
Full name | | interleukin 17 receptor A |
Aliases | | ,CD217,CDw217,IL-17RA,IL17R,MGC10262,hIL-17R, |
Gene summary | | Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q11.1 |
Gene position | | 17565849 - 17591405 Map Viewer |
Gene orientation | | plus |
Gene size | | 25557 bp |
Gene sequence |
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OMIM ID | | 605461 |