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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for Apob (Mus musculus)
(Information is obtained from NCBI Gene database)
Entrez gene ID238055
Official gene symbolApob
Full nameapolipoprotein B
AliasesAI315052,MGC176318,apob-100,apob-48
Gene summaryThis gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100. Unlike the apoB-48 and apoB-100 structural equivalents in human, which are synthesized exclusively in the gut and liver, respectively, the mouse apoB-48 isoform is also found in mouse liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2179 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. [provided by RefSeq]
LocationChromosome: 12   Locus: 12 A1.1
Gene position7984483 - 8023645  Map Viewer
Gene orientationplus
Gene size39163 bp
Gene sequence