Entrez gene ID | | 24015 |
Official gene symbol | | Abce1 |
Full name | | ATP-binding cassette, sub-family E (OABP), member 1 |
Aliases | | C79080,Oabp,RLI,RNS41,Rnaseli |
Gene summary | | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8 C |
Gene position | | 82235639 - 82207341 Map Viewer |
Gene orientation | | minus |
Gene size | | 28299 bp |
Gene sequence |
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