Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ALOX5AP (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID241
Official gene symbolALOX5AP
Full namearachidonate 5-lipoxygenase-activating protein
Aliases,FLAP,
Gene summaryThis gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. [provided by RefSeq]
LocationChromosome: 13   Locus: 13q12
Gene position31309669 - 31338556  Map Viewer
Gene orientationplus
Gene size28888 bp
Gene sequence
OMIM ID603700