Entrez gene ID | | 245908 |
Official gene symbol | | DEFB105A |
Full name | | defensin, beta 105A |
Aliases | | ,BD-5,DEFB-5,DEFB105,DEFB105B, |
Gene summary | | Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 105, DEFB105A and DEFB105B, in tail-to-tail orientation. This gene, DEFB105A, represents the more centromeric copy. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8p23.1 |
Gene position | | 7681360 - 7679530 Map Viewer |
Gene orientation | | minus |
Gene size | | 1831 bp |
Gene sequence |
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