| Entrez gene ID | | 245973 |
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| Official gene symbol | | ATP6V1C2 |
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| Full name | | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 |
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| Aliases | | ,ATP6C2,VMA5, |
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| Gene summary | | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms. [provided by RefSeq] |
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| Location | | Chromosome: 2 Locus: - |
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| Gene position | | 10861775 - 10925236 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 63462 bp |
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| Gene sequence |
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