Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AKR7L (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 246181 Official gene symbol AKR7L Full name aldo-keto reductase family 7-like Aliases ,AFAR3,AKR7A4, Gene summary This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. This family member encodes a selenoprotein, which contains a selenocysteine (Sec) residue. The selenocysteine is encoded by a UGA codon that normally signals translational termination. Selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq] Location Chromosome: 1   Locus: 1p36.13|1p35-p36.1 Gene position 19600568 - 19592476  Map Viewer Gene orientation minus Gene size 8093 bp Gene sequence >AKR7L:complement(6272564..6280656):Length=8093 ATGTCCCGGCAGCTGTCGCGGGCCCGGCCAGCCACGGTGCTGGGCGCCATGGAGATGGGG CGCCGCATGGACGCGCCCACCAGCGCCGCAGTCACGCGCGCCTTCCTGGAGCGCGGCCAC ACCGAGATAGACACGGCCTTCCTGTACAGCGACGGCCAGTCCGAGACCATCCTTGGCGGC CTGGGGCTCCGAATGGGCAGCAGCGACTGCAGAGGTAACAGTGGCCCCTGATCCTCCCTC TGCACGGTGCAGAGCTGAGCCTGTCACCAGCCGTGCGCTGCCCCGCTCTCCCTGGCCCCG GGCAGCACCCACGGCTTCGTCCCCCACCCCATCCCTGTCCACACCGCAACTCTGGGAACC GCCAGTTCCTCAGGCACATCTAGCTCTGGACAACTGGATGGTGCTTTGTCCGGACTCCTT TTCTGTCGTCTTCTCTTCCGGGAGGTAGCCCAGCACCCTCACTGACGCCTGGATGACTTG GTCTTGCCTGGAATGACTTGGCTAGCCCCTCTCTGGAGCACGAAAAACATTGGAATCTAG CATTGTGCAGCTCCTGTCCCCACCTGTGCCCTTCAGGTGCCCTTGACGGGCCTGATCTGC AGAAATTCTGTTCTTATCGCCTGGCACAGTCCAAAATCAGAGTTTGGACCCAGCACACTA TCTGCTTCCTCCTACGCTCATGCCAGACTGCTCGGGTCCCTGGACTTTGCTCTGGTAACT CACCAGGGTGACAATGCCTGGGAGCCTTGGCAGCTCCCTCAGTGAGATGGGGAATTGGGT GTGGTACAGGGTCTCGCTGCCCTCTCTGTGGGATGCTCTGTCTGAGGCTATTGGAGAGAA ATGGACACTAACCCACTCCAGGAATCTCCAATTCTAGCGATGGCTGGGGAGCCGAGTGAG CCCTTCTTGGGAGGGACCCCGTGAAGAAAGATAGGATAGGAGTTTGCCAGGAAGAGTACA AGGGGCAAGGGCGTCAGGGCAGTGGGCATGGGTGTGGAAAGGCAAATGCGACTTGGCAAT GCCGCCGGTGCTGGGGGAAGCAGGTGTAGCCCGAGGGGAAGATGTGTGTAAAGGGGCAGG AGGAGCCGCCCTCAGTCTGATGCCATTTGCAGTGCTTAGGCCGATGCCTGGCAGGCACAT AGTGAGGGCTGGGAAATGTTAGCTGTTTCTTTGTTCTTAATATTAGCACCATTTGCCTCC TTCCACTCTGAGTGTCTGAGTGGAGTCTTGTCCATTTCTCCTCTGATTCACCACATGGTA CATCCCAAACAAAAGAGGCCTGTGCGTGCATTTCAGTGCCACACTCTTTCTAGATCACCT GGCTGCCACTCGGTGAGAGCTCTGATCTTATTTCCGGTCTTTTTTTTTTTTTTTTTTTGA TACAGGGTCTTGCTCTTTTACCCAGGCTGGAGTGCAATCATGGCTCATTGCAGCTTTGGC CTCTCAGGGCTCAAGCGATCCTCCCACCTCAGCCTCCTTAGTAGCTGGGACTACTACAGG CCTGTGCCACCACACCTGGCTAATTTTTTGTATTATTCATCGAAACCAGAGTCTCACTTT GTTGCCCAGGCTGGTCTCAAACTCATGGGCTCAAGTGATCCTCCTGCCCTGGCCTCCCAA AGTGCTGAGATTACAGGTGTGAGCCACCACAGATCTGCACCCTCTGCCTGGCCCTTATTT CTGATTTTTTTTTTGTTTACTTTTTTAATCCTTGTCTTCTGTCTTTGAGTCCAAGGTTGG CTGGTGAAAGTCCTCAGATCTCAGATCTGAAGTTAAGTTCACATTGAGAAGCAGAGGGGT GGTGGTGGAATGGAAAAATTCCAAATGAATAATTCATCAAACCTGCTCCCTCCCAGGTCT CAAGGGCTCTAGTGACTGCCCTCTTGCCAGCCTAAGTGACTTTCTAAGTGTGAAAAGTGG GAAGAGGACTCTCCACTCACCTGTTATTCCAGCCCACTAGGATCTAGGATTTTTTATTTT TATTTTTATTTTGAAATAGGGTCTCATTCTGTCATCCGGGCTGGAGTACAGTGGCATAAT ATTTGCTCACTATAGCCTTGATCTCCTAGGCTCATGTGATCCTCTCAACTCAGCCTCCCC AGTAGCTGAGATTACAGGCATGTACCACCATGCCTGGCCAAATTTTGTGTTTTTTGTAGA GATGGGGTTTCACCATTTTGCCCAGGCTGGTCTCAAATCCCTGGGCTCAAGAGATCCACC CTCCTGGGCCTCTCTCAGTGCTCGGCTTATGGGGGTGAGCCACTGTGCCTAATCTCCAAC TAAGATTTTTTTTTTTTGCGGGGGGGACAGAGTCTTGTTCTGGCACACAGGCTGGAGTGT AGTGAAAGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTTGTGCCT CAGCCTCTCCAGTAGCTGGGATTACAAGTTTGAGCCACTGAAACCAGCCTCCAACTAGGA TTCTTAATACGGGGCAGGGAGAAGAGTGTTAAGCTTACTTCTTCTTTTTTTTTTTTTTGA CAGTCTTGCTCTGTCACCCAGGCTTCACTGCAATGGCACGATCTGGGCTCACTGCAACCT CTACCTCCCAGGTTCATGCAATTCTTTTTTTTTTTCTTTTTTTTTGAGACAGAGTCTCGC TTTGTTGCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCC GGGTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCACCA CCATGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGATTTCACCGTGTTAGCCAGG ATGGTCTCGAACTCCTGATCTTGTGATCTGCCTGCCTCAGCCTCCCAAAGTGCCGGGATT ACAGGTGTGAGCCACTGCACCCGGCTGGTTCATGCAATTCTTGTGCCTAGCCTCCCAAGT AGCAGAGATAACAGGCGTGTACAACCACCCCCAGCTAATTTTTGTATTTTTAGTACAGAT GGGGTTTTACCATGTTGGCCAGCTTGGTCTCAAATTCCTGACCTCAGGTCATTTACCCAC CTCGGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCACATCCAGCCCTGAATTTT CATTTCTCTTTCCTCTCAGTGAAAATTGCTACCAAGGCCAATCCATGGATTGGGAACTCC CTGAAGCCTGACAGTGTCCGATCCCAGCTGGAGACGTCACTGAAGCGGCTGCAGTGTCCC TGAGTGGACCTCTTCTATCTACATGCACCTGACCACAGCGCCCCGGTGGAAGAGACACTG CGTGCCTGCCACCAGCTGCACCAGGAGGTGAGGGGACCCCTGAGCTCTGGGAGGTGGTCC ACTGCTGCTCTCCTTATCCTGATCCTAATGGTGAGAGCAGAGGCACCAGGGCAGTTCCAG GGTGGAGCAGGGAACAGCCCAACTCCCAGGGGCCCCACCCTGACCTCCCTTTCCTGGTCT GGGCTGCACTATGTTCTGACTGGAGCCTCACCCGAGCAGGGCAAGTTCGTGGAGCTTGGC CTCTCCAACTATGCCGCCTGGGAAGTGGCCGAGATCTGTACCCTCTGCAAGAGCAACGGC TGGATCCTGCCCACTGTGTACCAGGTGAGGGCCGGGGCTGCAGAGGCCAAGGTCTCCAGA ACTCCTGCTCATCCTGGGCTGTCTTTGCCCCTCTGACTGCCCCCATGCCCTCTGCATAGC AGCCACTCCCCTGCTGAAAGCCTGCAGATGGCTCCCAGGTACCCTCAGGATGCCATTCAA GCTCCTCAGGCTGGCCACTGGGCATCTGCTTCCTTCCTGCCTATCTGTGCACCTTGGACC CTTCCTTCCCTACCTTCCCCTGCACTCAGCCTGGAACAAGCCCTTCCCCCACCACCGCCC CTTCTGTGAGAGAATGGTTCAGGTCTCACATACGTGTCTCTTCCTCTGGAAGCCTTTCTA GATGGGCCCAGAAGACCCTGAGACCTCAGGTCCTTGTTTACCTCCTCATGATTCATTGCA CAAATATTTGCACACCTGCTTGGTGCCAGGCACTGGTCACAGAACTTTCTAGTCTATTAT GATTGCCTCATGACTCGATTATAACTGTTTATGCTTGACCTTACTACAAAATATTTGAGG GAAGGGACCTTGTCCTTTTAGCTTTTGAATCTAAATCTGACAACCAGCCCACAGTTGGTG CTCATGAAAGTTGGCAGAATGAATGAATTTTCCTAGGGCATAAGCCCCTTTCACCAGCAC CAGTAAGAATAAGTATATGCCCAGATGGTTAAAATCCTAGAATTGTTAAGGTCTGAAATA AGGGTTCTATGAGGGTAAATTTAGGTCCCTTCTTTTGACACATCCACCCTCTCCCCGGGG CCCTTCTCCTTACAGGGCATGTACAGCGCCACCACCCGGCAGGTGGAAACGGAGCTCTTC CCCTGCCTCAGGCACTTTGGACTGAGGTTCTATGCCTACAACCCTCTGGCTGGTACGTGG AGCATTCCTGGCCCTGACTCAGCCTATTCCCGACCCACAGATGCCCAGCCCAGGACCTGG GAAGAAGGGAGGGTTTGACAAGAGGCTGGGCTGCATCCTTCAGCCCTCCTGGGTCCCTGC CCCTCCCCTAGACCAGAGCCCTGAGGGATGTGGCAGCTTCTGGGGCACTCTGGGCCCGGG GGCTGATTGCTGCCTTCCCGCAGGGGGCCTGCTGACCGGCAAGTACAAGTATGAGGACAA GGACGGGAAACAGCCCGTGGGCCGCTTCTTTGGGACTCAGTGGGCAGAGATCTACAGGAA TCAGTTAGTTGGGGGTGCTTGATGTGGATGGCTGGGGTGGGGTCAGCTTTATGTGGAATG AAGTCCTGGGCTGCTCCTGGGGTAAGGCCTTTCCTCGCTGTCTGCACCTACTCCCCTGCA TTCCTTCAGGAATTCCCAAGCCCTCTGTGGGTTTTCTTGTTGTCTTGGGACCTCCAGGAG GAAAGGAGACTCCCTGGACCTCGGTGTCTTGAAGTCGTAGCTCTTTCCTGAGCAATCACC CGCTACAAAGGAAAGAAAGAGCCCTGGAAGGAGGTCCAGGAGGCCTGGGGCTGAGTCCTG ACCTGTCTCAGTGGCCTTCATGTCCGTAGGGGAAATGAGAGCAGGCTGCTGAGTTCTCAG GAATAAAGATTCGTTGAGGTCTCTGCTGAGGGGCCCAGCATCCTGGGTGGTTCTGATGCC CAGAAAAGTGAGAGACCTATGACTAGAGAGGACACCCGCCCCTCAGGGCTGCAGGGTGTG GGGTGGGGCAGTGGCCTTGGATGGCTCTTTGGTTGTGGCTTCCAGTGTGACCCTGATGGT ACTGACCCCTGTGCCACCATCCCCACTGAACAGCTTCTGGAAGGAGCACCACTTCGAGGG CATTGCCCTGGTGGAGAAGGCCCTGCAGGCCGCGTATGGCGCCAGCGCTCCCAGCATGAC CTCGGCCGCCCTCCGGTGGATGTACCACCACTCACAGCTGCAGGTAACCAGCGACCCTGG GTGCTCAGCTTCTTCCCTTCCAGGGGAACCAGCATTCATTACCTTCAGGTGAAGCCCAAA GCATTTGTTTTCTCGATTCCTCTGAAATTTCTTTCTTCCAACTCTCATAAACACTCTTCC CACTGGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCTGTTATGC CAGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACTTCTGCCTCCCAGACTCAAGC AATTCTCCTCCCCCAGCCTCCTGAGTAGCTGGGATTACAGGCACGCACCACTATGACCAA CTAATTGTTTGTATTTATAGTAGAGATGGGGTTTCGCCAAGCTGCCTATGCTGGTCTTGA ACTCCTGAGCTCAGACAATTCGCCCTCCTCAGCCTCTGAAAGTGCTGGGATTACAGGCGT GAGCCCCTGCGCTCGGCCTTCCCATTGGTCTTTGATGGTATCTGAGTGCCAGGCTTTGTA ATGAGGGCTTCACTGCAGGGATTTCATTATTCCTTCAGCTTTATGAAATGACTATCCCAG TGTTATTGATGAGGAAACTGAGTTTCACCCAGCTATGAAAGGGGAAGACATTTTAACACA GGTTCAACTGTAAAGCCCACTAGCCTCATCCTTTTGGTGGGAGCTGGAGTTTCCCTCTCT CAGTGCCTCATGTCTTCCTCACTTATATCCAACTCCAGCCTTAGATGTTGCAATAGTGTC TGGCATATATACAGTAGGTGCTCAATAAATGGGAGCTAAGTGCTCTACATAATTTTTCAC ACCCATAACCATGTTGAAAATAGAAAAGAGGATTGAATCTCAGAGAGGTTTAATAACTTA GCCGCGTTTACACAGCTGCTGGGGGGCAGAACTGGGCTGTGAATGTAGGTCTGTCTGGAA GCGTCGTGTGGCAGTAGGGGAAGGGATACAGGTTTTGCGTCACATGGGTACAGCTATCCA AGGCACCTTAAGTTCTTTCTGGACATATGGGATACAAGAGATCCCAAATCTCAGCAGGGA GGTGGCTGGGACAGCTGTGAGTGGAGTCGCTGTGCAGCAGAAGAGGGTTGAAGTCTGGCC GTCTCCCTTGCAGGGTGCCCACGGGGACGCGGTCATCCTGGGCATGTCCAGCCTGGAGCA GCTGGAGCAGAACTTGGCAGCGGCAGAGGAAGGGCCCCTGGAGCCGGCTGTCGTGGACGC CTTTAATCAAGCCTGGCATTTGTTTGCCCACGAATGTCCCAACTACTTCATCTAAGCTCA TTGTGGCTCAGGCTGCCCAAGGCTTTTCTGTCAACTCTTTTGCTCTCTCCCGCTTTGTCT AATTTAGAACTGCCTCACTAAATTCTTAGGGATGGAAGTATTTGGAAAAAAACCTAACAG TAGAGTCACCACCTAAGGAAGAATAAAATCTCCCAGGGTGCTGTGTGTTAGTCTGTTTGC GTTGCTATAAAAGAATACCTGAGACTGGGTCATGTATAAAGAAAAGAGGTTTCTTTGGCT CACAGTTCTGCAGTCTGTACAAGAGGGTGTGGTGCCGGCATCTGCTCTTGGTGAGGGCCT CAGGAAGCTTAGAATCATGGCAGAAGGGGAAACGGAGCCAGCGTGTCACATGGTGAGAGA GGGAGCAAGAGACAGACAGGGGAGGAAATTCACACACTGATGGTGGGGATGTAAAATGGT ACAACCAGTTTGGAAAACAGTTTGGCAGTTTCTCAAAGGATTAAACATAAAATTACCATA GGATTCAGCAGTTCCACTTGTGGGTATGTAGCCAAGAGAAATGAAAACATATCTCCCCAC AAAAAAACTTGGGTATGAGATTTCACATTATCATTGCTCATAATAGCCAATAAGTAAAAA CAACCCAAATGTCCAAGAATGAATAAATGGATAAACAAAATATGGTATATTTATACAACA GACTATTATTCGGCCATTAAAAAAAAAAAAGAGTGGCTGACACCTGTAATCTCAGCACTT TGAGAGGCCAAGGCAGTAGGACTGATTGAAGACAGGAGTTCCAGACCAGTCTGGGAAACA AAGCGAGACCCTGTCTCCACTAAACATAAAAACAAAATTACTGGGGCCCCATGGCACACA CCTGTAGTCCCAGCTGCTCGGGAAGCTGAGATGGGCGGATTGCTTGAGCCCAGGTATTCA AGTCTGGAGTGAGCTATGACTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCAAACCCT GTTTCCAAACAAACAAACAAACAAACAAATACACAGACAGAAGTAGTTAAACATCTACAA GGTAAGTGCATCTTGAAGACGTGTTAAGTTAAAGAAGCCAATTACAAAAGGTTTCACGTT GTATGATTTCGTTTATATGAAATGTCCAGAATAGGCAAATCTGTTTGAGAGAGAGAAAGT AGATGAGTACTTGCCTAGGACTGGGAGGAGGATTGCGAGGAAATGGAGATTCACTGCTAA TGAGTACAGGGTTTCTTTTGGGGGCGCTTATGAAGATGCTCTGAAATTGATTGTGATGGT TGTACAACTCTGAATACATGAAACAGCATTAAACATCACTTTAAGTAAGTCAA OMIM ID 608478