| Entrez gene ID | | 246334 |
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| Official gene symbol | | Tp63 |
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| Full name | | tumor protein p63 |
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| Aliases | | Ket,P73l,Tp73l,Trp63 |
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| Gene summary | | This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Both alternative splicing and the use of alternative promoters result in multiple transcript variants encoding different protein isoforms. |
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| Location | | Chromosome: 11 Locus: 11q23 |
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| Gene position | | 76900621 - 77200250 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 299630 bp |
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| Gene sequence |
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