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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IL27 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 246778 Official gene symbol IL27 Full name interleukin 27 Aliases ,IL-27,IL-27A,IL27p28,IL30,MGC71873,p28, Gene summary The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq] Location Chromosome: 16   Locus: - Gene position 28518155 - 28510683  Map Viewer Gene orientation minus Gene size 7473 bp Gene sequence >IL27:complement(28450683..28458155):Length=7473 GACCAAAGAGGCTGGGCCCCGCCATGGGCCAGACGGCAGGCGACCTTGGCTGGCGTGAGT TTGAAGCCAGGGGTGGGGGGCTTGGTTGAGTTTGGGCAGAGAATGGACGAGCTTGGCTGG TGCAGATGGGGGGTCGAGAGCTGAGAGCAGCAACTTGGCCAAGACTGAGGATTCGGCTGG CTGCTGCATGGGAAGGGAGGCTGGCATGACTGGGTGGGGGCCTGGGGCAGTGGGGTGGTG GTCTGACCCAGGGCTGGGCAGAGGATGAGAAGGAGGCCTTGGCTAGTGGGAATGGGGAGG GTTGGACCAGCAATTTGACAAGGACCAGGTCTAGGCAGATAAATGAAGAGTTTGGAGTGA ATAAGCAGAAGCCAAACAGCTTGGCTAAGACTGAGAATGGGGCCGGCTGGAGGAAGAGCA GAACGAGGTGCTGGCACAAGTGGAGCACTGGGACCAAGATGTCAGCAGCCTCACTGGGTC AAAGGTCTTTAGTTTGATGTTGGAAAGAGGTCCAATCTGCGGCTGGTGGCTGCAGAACTC AGGGGCTAGAACCAGAGCAGTAGGCAGTGGAGAAGGTAACATGCCACGTAGGGCAGGTAG GGACCAAAGGCTGGAGGATGGAGACAGAGCCTTCAAAGGCCAGAGCCAATGACCCAGGAT CAGCTGCAGAGGGTAAGGAGGGGGTCTGGGGTCTCCAGAGGTCAGGTTGGAGATGGCACA GCTCACTTACGGTTGGGCTTGATCCACCAGGGCCTGGGGGCACCCACCCTGTCCCCAACA TTGAGCTAGGAAGAACCCCACTCTGCCTTAAGTCTCCAGGATGTCAGAGGGTCCGAGTGG CCCCAAAACCAGGGAGTCTGAATGCCAGAGATCTTACGTTAGGCATCGCCCACCACATCT GCAAGCCCACGAGGGAGGTAGATGTCCCTAGAAGCTCCCCTTCACCTTTATCAGGGGACA TTTCGAAGAGCAGAGCCCAGGGGTTAGAGATTGAGAGAGGACAGGGAAGAGGCAGGGAGA GAAGGGAGAGCAGGATGGACTTCGGGCCAGTTTTGGTTTGTGTTTCGAGGAGAATTGTGT AACTCTTGTGCTTGCTAGATTTCCTCTCCCTGAGGGGGAAATTGATGAATGCTGCCCTCT TCCTAGAGCGCCCATCCGCTGCCCCTCTTTCCAGGAAAACACAGGTCAGGAAGCACACTC GGAATTCAGCCATTCTGGGCTGGGCGCAGTGGCTGATGTCTGTAATCCCAGCACTTTGGG AGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACACGGC AAAACCCCTCTCTACTAAATATAATAAAAATTAGCCAGGCGTGGTGGCTACTCAGGAGGC TGAGGCAGGAGAATTGCTTTAACCTGGGAGGTGAAGGTTGCAGTGAGTCGAGATCGCGCC ACTGCACTGCAGCCTGGGTGACAGAGTGAGAATCTGTCTTAAAAAAAAAAAAGCTCCCAT ACTGTGGATTCGCCCCAGGCAGGTTACCCTGCTAGGATCCACCTGCCGTGGTGGAAACTG GACAAACCTGTCCTTTTGACTCCCTGGAATAGAGCCTCTGGCATTGCCAGCCCATCCCTG GGGACCTCATGGCCAGTTCAAGCCATCAGAGCCGCTTGGCTGAGCCCAAAGAATCCTTGC CAGAACATGGTGTGCCCACTCCTGGGGCAGATGGCTGCCTCCCTCTGCATTCTCTGGGGA AAACCCATGGGCTCTGCATTTGGAAAAACCTGGAATCCAGTCCTGGCTTCCCACCTTCTG GCTATTTGACCTTGGGCAAGTCAACCTCACTGAGCCTCACCTGCAAATTGGGGAGAACAA TAGCACTGAGGCTGCCACACGTGGTTGTGCAGGTTGCTCACTGAAAAAGGCATTTGGCCA AGGGAGTTTATGGGGGTCAAAATCCAGTCTCTGTCCCGGCACAGTGGCTCATGCCTGTGA TCCCAGCAATTTGGGAGGCTGAGGCGGGAAGATCTCTTGAGGCCAGGAGTTCAAGACCAG CCTGGGCAACATAGTGAGACCCTGTCTCTACAAAAAAATAGAAACAGTTAGGCACAGTGG TGTGTCCCTGTGATCCCAGCTACTTGGGAGGCTGAGGCGAGAGGATCACTTGAGCCTAGG AGTTCAAGGCTACAGTGAGCTGTGATCACACCACTACACTCCAGGCTGGGTGATAGAACA GAACTCTGTTTCAAAAAAAAAAAAAAAGGATCAGGCTTCTGGTCTTTTTGCAAAAGTGGG CACACCATGCGGAGATGCCATATGGGGGCCGTGCTGGCTGCATCGTGGGGTTTTGTTTTG TTTTGTTTTGTTTTGTTTTTTTGAGACAGAGTCTGGCTCTGTCGCCCAGGCTGGAGCACA GTGGTGTTAGCTCACTGCAGCCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAACC TCCTGAGTAGCTGGGATTACAGGCATGCACCACCACGCCCAACTAATTTTTGTATTTTTA GTAGAGACAGGGTTTCGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGGCCTCAGGTGAT CCGCCCGCCTCGGTCTCCTAAATTGTTGGGATTACAGGTGTGAGTCACCGCACCCAGCCT CCATTGTGGTTTTGAGGAGGCAGAGGAATGATGCTGGTCAAAGTGCCTGCACCGTGCTCA CAGCTAGCACAGGCTCAGAAAAGGCATGTTCCCTTCCTTCTCAAGCTCTCTCCCTGTCTT GCCACCCTCTTCCCATCTCTCCAGGGCTCAGCCTGTTGCTGCTTCCCTTGCTCCTGGTTC AAGCTGGTGTCTGGGGATTCCCAAGGCCCCCAGGGAGGCCCCAGCTGAGCCTGCAGGAGC TGCGGAGGGAGTTCACAGTCAGCCTGCATCTCGCCAGGAAGCTGCTCTCCGAGGTTCGGG GCCAGGCCCACCGCTTTGTAAGTCCCCCTAATGCAGCTGGCGCTGGAGATGGGCAGACCC CCAATCCCTTCTGGCCCCCACTAACAGACCTTGCCCCCCAGGCGGAATCTCACCTGCCAG GAGTGAACCTGTACCTCCTGCCCCTGGGAGAGCAGCTCCCTGATGTTTCCCTGACCTTCC AGGCCTGGCGCCGCCTCTCTGTGAGTGAGGGCTGGTGGAGTGGGGCGGGAAGCTTGTGAT AGGCTGGGGCCAGGGTGCAAGATGAGGCTGGAGATTGAGCTGGAGATGCATTGGGGATAG AACCTGGATAAGGCTGAATATGTCATTGGACATAGAGATGAAAGACAGGCATGGTGACTT ACACCTATAAACCCAGCACTTTGGGAGGCCCAGGTGGAAGGACTGCTTGAGGCCAGGAGT TCAAGACCAGTCTGGGCAACATAGTGAAACTTTGTCTCTACAAAAAAAAATTTAAGAGTT AGCCAGGCATGGTGGTGTACACCTTTGGTCCCAGCTACTCAGGAGGCTGACATGGGAGGA TTGCTTGAGCTCAGGAGTTGGAGGCTGCAGTGAGTTATGATCCTGGACTCCAGGATGGAG AACAGAGGGAAACCCTGTCTCAGAAAAATAAATAAACTGCCAGGCGTGGTGGCTCATGCC TGTAATCCCAGCACGTTGGGAGGCTGAGGAGCACGGATCACCTGAGGTCAAGAGTTCAAG ACCAGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAAATACAAAAATTAGCTGAG CGCAGTGGCTCACGACTGTAATCCCAGCACTGTGGGAGGCTGATGTGGGTGGATCACCTG AGGTCAGGAGTTCGAGACCAGCCTGACCAACATGAAGAAACCCCACCTCTACTAAAAATA CCAAATTAGCCGGGTATGGTGCTGTGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGC AGGAGAATTACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGATGAGATCGCGCCACTGCA CTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCAAAACAAACCAACAATAAAGATGAAG CTGGAATAAGGAAGTGGGGTTGGGAAGAGGTAAGAGTGGAGCTAGGCATGGAACGCGGCA GGCATGGGACTGGAATGAGGCTGGAGACAGATCACAGCAGCATGGAGGGTGGGTGGAGGT GGCACTGGGGGTGAGAATGCGGATAGTTAGAGATGAGAAGGTGATGATGAGGGTGAACGT TAAGCATGGGATGGAGAAGGGATGGGGATTGCTGGTGGGGAAGGGAATGGAATAGGGTTA GGAATGAGGTTGGAGATGGGATGGAAAGATGGAAAGAGTGAGTCTGGGCACATGGAGGAA GGATGGAGTTGGGGTTAGGAATGGGAATGAGGCTGAAGATGGGATGGAAACACATGGGCA GGAGGTATGATGGGATGGTGGAGGAGGGAAGGGAACAGGGCTGTGGATGGAGAGTGCTTC AGGGACTGAGAGGGGGTGGGTTAGAGAAGATCATTGGCATAGGAGTGAAAGGGAGGCTGG AAAAGGAGATGGGACAAATGTCCCAGACAGTGGAGATGGAAGGAATGGGGACACAGCTGG GCTGAGGTGGGGGAAGAGCTACAGGGATGGACTGGAGGCTGGAGCGTGGAATGGGAAGGA GACCCGGATAGGGAGGGGGTGGGTGTGATATGGCCATCCTTGGCCTGTGGACCTTTCCTG ACCATCTCCCTCCCCTTCAGGACCCGGAGCGTCTCTGCTTCATCTCCACCACGCTTCAGC CCTTCCATGCCCTGCTGGGAGGGCTGGGGACCCAGGGCCGCTGGACCAACATGGAGAGGA TGCAGCTGTGGGCCATGAGGCTGGACCTCCGCGATCTGCAGCGGCACCTCCGCTTCCAGG TAGAGCCCGGCCACCCTCCACCACCCCAGACCACGTGGGAAAGAAGACTCGCTGGCTCAT TCAGTGATCCCATGCTCTGAGTGTGTGTGAGTGTGAGAGTGTGAGTGTGACTGAGTGTCC ATGAGTGTGTGGGTTCATGAGTGTGAGAGTGACTGTGTGGGTCCGTAAGTGTGGGAGAGT GAGTGTGACTGTGTGGGTCCATGAGTGTGACAGTGTGACTGTGAGAGTGTGTGAGTGTGG GTCTGTGAGTGTGAGAGTGTGTGGGAGTGACTGTGAGTGCATGTGGGTCTGTATGAGTGT GAGCATGACTGTGTGTGAGGGTGTGGGTCCGTGAGTGTGAGAGTGAGTGTGTGGGTCTGT GTGAGTGTACCTGACTGTGAGAGTGTGTGGGTGTGACTGTGAGTGTGTGTGTGGGGGGGC TGTATGAGTGTGAGCATGACTGTGTGTATGTGCGTCCGTGTGTGAGTGTGACTGTGAGTG TGTGGGTCTGAGTGTGAAAGTGTGTGGCTGTGAGTGTGTGAGTGTGTGGGTGTGACTGTG AGTGTGTGTGGGTCTGTATGAGTGTGAGCGTGACCGTGTGTGTGTAGGTCCATGAGTGTG AGACTGTGAGTGTATGGGACTGTGAGTGTAAGAGTGTGGGAGTGTGTGGGTGGGTGTGTG AATGTGAGTGTTGTGAGTGTGAAAGTGAGGTGTGTGGGTGAGAGTTTGGGTATAGGTATG TCAGTGTGTGAGGATGAGTGTGAGTGTGAGAGTATGTGGGTACGTGAACGATTTTTTTTT TTTTCTGAGACTAAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGCGGTGCGATCTCAGC TCACTGTAACATCTGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGC TAGGACTACAGGCGTGCACCATCATGCCTGGCTAATTTTTTTGTATTTTTAGTTTCACCA TGTTGGCCAGGCTGGTCTCAGACTCCTGACCTCGCGCTCTGCCCGCCTCGGCTTCCCAAA GTGCTGGGATTACAGGCGTGAGCCACTGTGCCCAGCCATGAATGTGTTTTGTGTGAATGT GACTGTATGGGAATGAGTGTGGGTGCGTTGTGAGAATGAGTATGTGTGTGAGTGTGTGCG TGTGTGCAGGCGCACACACAGCCACACCAGGCCCTGGTGCTGCCCCTCAATCTTCACATT CTCCTGGGGCTCTATCTTCAACAGGAGGCCATTGGGCTGTGAGGTCACTCGGGGTGTGTC CTGAGTGCCCAGCACAGCGTCTGCCTCCTGTTTCCTTTCTCCCTCTGATTCTCTGATGTC ACCCAGATCCTCCAGAACCTTTCAAAGGGAAATCAGAATTTTACACTTAATGAAATGAGA ATAGAAAATGCAAGCAGCAGGGCTGGGCGTGGTGGCTCACGCCTGGAATCCCAGCACTTT AGGAGGCCAAAGCGGGTGGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACAT GGTAAAACCCCATCTCTACTAAAAATACAAAAATTAGTCGGGCGTGGTGGTGCGCGTCTG TAGTCCCAGCTACTCAGGAGGCTGAGGTAGGAGAATTGCTTGAACTGGGGAGACAGAGGT TGCAGTGAGCCGTGATCACCCCACTGCACTCCAGCCTGGGCGACAGAGCGGGGCTCCCAA GAAAGAGAGAGAGAGAGGAATGGCAAGCAGCAGGGAATCTGAGCTATGTCACCCTCTGCC TGTTGCTGACCCGACCCAAAAGCAACTTTCACAGCAGAGAGAAACTTCCTGAACCCCACG CCTCGGGGCAGTCCTTGGGGTGATCTAGCTCTGTGAGCATCCTCTTGCTCCTTGACTTCC ATTTTCTCGAACTGAAAGATCAGGTGAGACGCGTTAGCAGGTGACATCATGGAAGATCAA GCAGGGAATGTCCGGGGAAATCATGACCTTGTGGTCACTGATGTCATTGGGAACCGCTGG GCATGAATAGGGAATGAGGATTCCTCTCAGGTTCTCGGCCTGGCCCCTCCCTGACCCATG GCCTCTCCTCACAGGTGCTGGCTGCAGGATTCAACCTCCCGGAGGAGGAGGAGGAGGAAG AGGAGGAGGAGGAGGAGGAGAGGAAGGGGCTGCTCCCAGGGGCACTGGGCAGCGCCTTAC AGGGCCCGGCCCAGGTGTCCTGGCCCCAGCTCCTCTCCACCTACCGCCTGCTGCACTCCT TGGAGCTCGTCTTATCTCGGGCCGTGCGGGAGTTGCTGCTGCTGTCCAAGGCTGGGCACT CAGTCTGGCCCTTGGGGTTCCCAACATTGAGCCCCCAGCCCTGATCGGTGGCTTCTTAGC CCCCTGCCCCCCACCCTTTAGAACTTTAGGACTGGAGTCTTGGCATCAGGGCAGCCTTCG CATCATCAGCCTTGGACAAGGGAGGGCTCTTCCAGCCCCCTGCCCCAGGCTCTACCCAGT AACTGAAAGCCCCTCTGGTCCTCGCCAGCTATTTATTTCTTGGATATTTATTTATTGTTT AGGGAGATGATGGTTTATTTATTGTCTTGGGGCCCGATGGTCCTCCTCGGGCCAAGCCCC CATGCTGGGTGCCCAATAAAGCACTCTCATCCA OMIM ID 608273