Entrez gene ID | | 24851 |
Official gene symbol | | Tpm1 |
Full name | | tropomyosin 1, alpha |
Aliases | | Alpha-tm,Tma2,Tmsa |
Gene summary | | This gene is a member of the tropomyosin family and encodes a protein that heterodimerizes with a beta subunit, binding actin in both muscle and nonmuscle cells. In both smooth and striated muscle cells, it plays a role in calcium dependent-regulation of muscle contraction. In nonmuscle cells, it stabilizes cytoskeleton actin filaments. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q24 |
Gene position | | 71331303 - 71358062 Map Viewer |
Gene orientation | | minus |
Gene size | | 26760 bp |
Gene sequence |
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