Entrez gene ID | | 24883 |
Official gene symbol | | Wt1 |
Full name | | Wilms tumor 1 |
Aliases | | - |
Gene summary | | This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It plays an essential role in the normal development of the urogenital system, and the human gene is mutated in a small subset of patients with Wilm's tumors. Authors of PMID:7926762 provide evidence that Wt1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q32 |
Gene position | | 90529703 - 90577279 Map Viewer |
Gene orientation | | plus |
Gene size | | 47577 bp |
Gene sequence |
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