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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ALPP (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 250 Official gene symbol ALPP Full name alkaline phosphatase, placental (Regan isozyme) Aliases ,ALP,FLJ61142,PALP,PLAP, Gene summary There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq] Location Chromosome: 2   Locus: 2q37 Gene position 233243348 - 233247599  Map Viewer Gene orientation plus Gene size 4252 bp Gene sequence >ALPP:83452766..83457017:Length=4252 TCAGCCAGTGTGGCTTCAGGTCAAGAGGCTGGGCAGGGTCAAGGTGGCAACGAGGGGAGA AGCCGGGACACAGTTCTCCCTGATTTAAACCCGGGCAGCCTGGAGTGCAGCTCATACTCC ATGCCCAGAATTCCTGCCTCGCCACTGTCCTGCTGCCCTCCAGACATGCTGGGGCCCTGC ATGCTGCTGCTGCTGCTGCTGCTGGGCCTGAGGCTACAGCTCTCCCTGGGCATCATCCCA GGTAATGAGGCTCCCCGAGCTGCCCCTACACAACACACACACAGGGCACCCCCCAGCCCA GGCTGACCTGATTTTTGCTCTCCCCCTGGCCAGTTGAGGAGGAGAACCCGGACTTCTGGA ACCGCGAGGCAGCCGAGGCCCTGGGTGCCGCCAAGAAGCTGCAGCCTGCACAGACAGCCG CCAAGAACCTCATCATCTTCCTGGGCGATGGTGAGTGAGCCAGGCCTTCCAGCCCTGCAG CCCTCACAGCCCCGGCGCCCGGACCCTCAGTGGTTCCAGGAGAGCCCTGGGGCCCAAGCC TCACACATTTCTGTTCCTTCAGGGATGGGGGTGTCTACGGTGACAGCTGCCAGGATCCTA AAAGGGCAGAAGAAGGACAAACTGGGGCCTGAGATACCCCTGGCCATGGACCGCTTCCCA TATGTGGCTCTGTCCAAGGTAAGTGCTGGGCTACCTTAGAGTCCTCCAAGCACAGAAGGG GAATCCTGGCTATGGAGTGTGGTAGGAGGGAGGGACCCTAAACAGCTGGGGCTCCAGTAA GGAGTTAGAGGCAGTTGGAATCCCAGAGGACAGAGATCAGGGTCTGGGTCTCCGTGTCTG CCCCAGAGAAGAGCTCAGAGTGTCTCTGTCCCCAGACATACAATGTAGACAAACATGTGC CAGACAGTGGAGCCACAGCCACGGCCTACCTGTGCGGGGTCAAGGGCAACTTCCAGACCA TTGGCTTGAGTGCAGCCGCCCGCTTTAACCAGTGCAACACGACACGCGGCAACGAGGTCA TCTCCGTGATGAATCGGGCCAAGAAAGCAGGTGAGCTGGGGCCCGCTGCTGGGTCACGGC CAGGTCACAGACGTTGGTCACATATACTGACCTCTGACACCCTTAGGGAAGTCAGTGGGA GTGGTAACCACCACACGAGTGCAGCACGCCTCGCCAGCCGGCACCTACGCCCACACGGTG AACCGCAACTGGTACTCGGACGCCGACGTGCCTGCCTCCGCCCGCCAGGAGGGGTGCCAG GACATCGCTACGCAGCTCATCTCCAACATGGACATTGACGTGCGACCCCCAGGCCAAGGG CTGGGGCTGGGCAGAGAGTAGCAGGGAGGGGGCACTAGCTCAGACCCAGGCAACCAAAAG CCTTATCTGGGCCAGCAGGGTCTGGAGGTGGGGTTGTGGGCGTAGAAGGTGCAGCCCAGG CTGGGCCATTCCCACAGCCTTGGGGAGGGGAGTCAGGGGCTGTGCATGAGGAGGGGGCAC GGGGCCAGCCAGGGCCCCAAATCCACCTGCCCCATCCTCTGTTCCCAGGTGATCCTAGGT GGAGGCCGAAAGTACATGTTTCGCATGGGAACCCCAGACCCTGAGTACCCAGATGACTAC AGCCAAGGTGGGACCAGGCTGGACGGGAAGAATCTGGTGCAGGAATGGCTGGCGAAGCGC CAGGTGATGGGGGCTGGCGGGTGCAGGGGGCACAGCAGGGGGAGGGCAGAGGTGTGGGGC TCAGGGCTGTGGGCTGAGGCCTGGCTCTCTCCCTCCCCACAGGGTGCCCGGTATGTGTGG AACCGCACTGAGCTCATGCAGGCTTCCCTGGACCCGTCTGTGACCCATCTCATGGGTAAT GACCCCCTTCCTGCCCTGGCATCCCTCAGATGGCCTCAGATGGCACCTTCTGAGCCTGTG TGCACATCCGCCAGCACCCGCCCACCCCCAGCCTGCCAGTCACCACAGGACCCCTTGTCC CACAGGTCTCTTTGAGCCTGGAGACATGAAATACGAGATCCACCGAGACTCCACACTGGA CCCCTCCCTGATGGAGATGACAGAGGCTGCCCTGCGCCTGCTGAGCAGGAACCCCCGCGG CTTCTTCCTCTTCGTGGAGGGTGCGTGGTGGCCCCTGGGGAGTGGGGGTTGGGGGTTGGA GCAGGGCAGGCTCAGCATCTCCCCCCTCTGGCCTTCCTGCAGGTGGTCGCATCGACCATG GTCATCATGAAAGCAGGGCTTACCGGGCACTGACTGAGACGATCATGTTCGACGACGCCA TTGAGAGGGCGGGCCAGCTCACCAGCGAGGAGGACACGCTGAGCCTCGTCACTGCCGACC ACTCCCACGTCTTCTCCTTCGGAGGCTACCCCCTGCGAGGGAGCTCCATCTTCGGTAGGC CTGGGGAGAGTGGCAGGTGCTGCTGCAGCAATTAAGTGGGTGAAATCTGAGCCTCAGTCT CCTCCTCTGTCAAATGGGAGTAATGCTGGCACCAGCCCTGTAGGGTCTCCTGAGGACTAA GCCCCTGACCAGGCAAAACGTGGCGGTGCCTAGCACGTGGGAGACACTCCACAGCTGTGT TCAGCTCAACCACAGGGACCCCTCTCTCTGCAGGGCTGGCCCCTGGCAAGGCCCGGGACA GGAAGGCCTACACGGTCCTCCTATACGGAAACGGTCCAGGCTATGTGCTCAAGGACGGCG CCCGGCCGGATGTTACCGAGAGCGAGAGCGGTGAGTGCCGCGGGGTGGCCCCCTGAGGGG GACCAGGGTGCCAAGGATGGGGGGCTGGCGGGAAGGGGTCACCTCCTGTCTGCCTGGAAC TGAATGAACCCTCCTACCGGAACTGAACCCTCCAACCAGGGAGCCCCGAGTATCGGCAGC AGTCAGCAGTGCCCCTGGACGAAGAGACCCACGCAGGCGAGGACGTGGCGGTGTTCGCGC GCGGCCCGCAGGCGCACCTGGTTCACGGCGTGCAGGAGCAGACCTTCATAGCGCACGTCA TGGCCTTCGCCGCCTGCCTGGAGCCCTACACCGCCTGCGACCTGGCGCCCCCCGCCGGCA CCACCGACGCCGCGCACCCGGGGCGGTCCGTGGTCCCCGCGTTGCTTCCTCTGCTGGCCG GGACCCTGCTGCTGCTGGAGACGGCCACTGCTCCCTGAGTGTCCCGTCCCTGGGGCTCCT GCTTCCCCATCCCGGAGTTCTCCTGCTCCCCACCTCCTGTCGTCCTGCCTGGCCTCCAGC CCGAGTCGTCATCCCCGGAGTCCCTATACAGAGGTCCTGCCATGGAACCTTCCCCTCCCC GTGCGCTCTGGGGACTGAGCCCATGACACCAAACCTGCCCCTTGGCTGCTCTCGGACTCC CTACCCCAACCCCAGGGACTGCAGGTTGTGCCCTGTGGCTGCCTGCACCCCAGGAAAGGA GGGGGCTCAGGCCATCCAGCCACCACCTACAGCCCAGTGGGTACCAGGCAGGCTCCCTTC CTGGGGAAAAGAAGCACCCAGACCCCGCGCCCCGCTGATCTTTGCTTCAGTCCTTGAATC ACCTGTGGGACTTGAGGACTCGGGATCTTCAGGACGCCTGGAGAAGGGTGGTTTCCTGCC ACCCTGCTGGCCAAGGAGGCTCCTGGGGTGGGGATCACCAGGGGGATTTTGACACAGCCT TCGGCTGCCCCCCACTAAGCTAATTCCACACCCCTGTACCCCCCCAGGGGGCCCTCTGCC TCATGGCAAAGGCTTGCCCCAAATCTCAACTTCTCAGACGTTCCATACCCCCACATGCCA ATTTCAGCACCCAACTGAGATCCGAGGAGCTCCTGGGAAGCCCTGGGTGCAGGACACTGG TCGAGAGCCAAAGGTCCCTCCCCAGACATCTGGACACTGGGCATAGATTTCTCAAGAAGG AAGACTCCCCTGCCTCCCCAGGGCCTCTGCTCTCCTGGGAGACAAAGCAATAATAAAAGG AAGTGTTTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAGGAGA TGGAGACCATCCTGGCTAACACGGTGAAACCCCTTATCTATGCGCCTGTAGTCCCAGCTA CCCAGGAGGCTGAAGCAGGATAATCGCTTGAACCCGGGCGGCGGAGATTGCAGTGAGCCG AGGTCATGCCACTGCACTGCAGCCTGGGCGACAGAGCGAGATTCTGCCTCAAAAATAAAC AAATAAATTTTAAAAATAAATAAATAATAAAAGGAAGTGTTAGACAATGTAA OMIM ID 171800