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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FUT3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 2525 Official gene symbol FUT3 Full name fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) Aliases ,CD174,FT3B,FucT-III,LE,Les,MGC131739, Gene summary The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq] Location Chromosome: 19   Locus: 19p13.3 Gene position 5851485 - 5842899  Map Viewer Gene orientation minus Gene size 8587 bp Gene sequence >FUT3:complement(5782899..5791485):Length=8587 TCTGTTCCCACTTCCTCCCCGCCCCAGGAAACCTGCCATGGCCTCCTGGTGAGCTGTCCT CATCCACTGCTCGCTGCCTCTCCAGGTAAGTTATCCCATTCTACCTTTTCCCCCCACCCA GAATGCCTGGGAGACCTCCCAGGAAAGGCTTCCTGGCTCCGTCCCTCCTCCCCTCGGCCC CCATCCTATGGGCCCTGATTCATGATGTGGCTGGGCTGGCACAAAATCCCGGTGGAGAGT CACCAAACTGTCCATGACCTGGAATGTGGCCAGCACCCCCTAGTCACAGGCAGGGGTCTT TCTGGGTGTGGCATGCACCACCGTTGGGGAGGACATGGAAGGTTCTGGGTGATTTGCCAA ACCGGAAGGAAAGAGTGACGTTTGTCTCTCTCTCTGGCAGAGCTCTGGAGTGGAGTCCCC TCTGCACCCCAACCCCATCAACAGCCTCCCCCCACTCATCTTTTCTGGCCTTGGATTCTC TCTGGCCCTGCCCTGCCTGGGGTGGACTTAAGATGCATTTTTTTTTTCTTTTTCTTTGAG ACAGAATCTTGGTCTGTTGCCCAGGCTGGAGTGCAGTGATGCAATCATGGCTCACTGCAG CCTCAGACTCCTGGGCTCGAGTGACCCTCCTGCCTCAGGCTCTGGAGTAGCTGGGACTAC AGGTGTGTGCCACCTCACCTGGATACTTTTTAATTTTTTTTTCTTTTGTAGAGATGGGGT CTCACTATGTTGCTCAGGCAGGACTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGA GTCTTGCTGTGTCGCCCAGGCTGGGGTACAGTGGCATGATCTCGGCTTATTGCAACCTCT GCCTCCCTCGTTCAAGCAATTCTTGTGCCTCAGCCTCCTGAGTAGCTGGGATTAAGGTGC CTGCCACCACACCTGGCTAATTTTTTATTTTTAGTAGAGACAAGATTTCACCATGTTGCC AAGGGTGGTCTCAAACTCTTGACCTCAGGTGACCTGCCCACCTCAGCCTCCGCAAGTACT GGCATTACAGCCATGAGCCATTGCACCCGGCCAATCAGGCAGGTCTTGAATTCCTGGGCT CAAGAGATCTGCCCACCTCACTCTCCGAAACTACTGGGATTACAGGCATGAGCCACCACG CCCAGCTATTTTTTTGCTTTTTGCTTCCTGATCTTTGTGATGTCTCAGCAGAGTAGCATT TTTTAATCTTTTTCTAGGAAAAAATATCTTGGGTTCAACTGGGGTGGGATCTCAGTCCTC ATCGCGATCTCACATGTCTGTGTGAAGAGACCACCAAACAGGCTTTGTGTGAGCAACAAG GCTGTTTATTTCACCTGGGTGCAGGCAGGCTGAGTCCGAAAAAGGAGTCAGCAACGGTGG TGGGATTATCATTGTTCTTATAGGTTTTGGGATAGGCAGTGGAGTTAGGAGCAATGTTTT GCAGGCAGAGGGTGAATCTCATAAAGTACATTCTCAAGGGTGGGGAGAATTACAGAGAAC CTTCTTAAGGGTTGGGGGGAGATTACAAAGTACATTGATCAGTTAGGGTAGGGCAGAAAC AAATCAATGGTGGAATGTCATCAGTTAAGGCTATTTTCACTTTTTTTGTGGATCTTCAGT TGCTTCAGGCCATCTAGATGTATACGAGCAGGTCACTGGGGATATGATGGCTTAGCTTGG GCTCAGAGGCCTGACATTCCTGTCTTCTTATATTAATAAGAAAAATAAAACGAAATAGTG GTAAAGTGTTGGGGTGGCAACAATTTTTTGGGGTGGTATGGAGAGATAATGGGCGATGTT TCTCAGGGCTGCTTCGAGCGGGATTAGGGGTTGGTGTGGGAACCTAGAGTGGGAGAGATT AAGCTGAAGGAAGATTTTGGGGTAAGGGGTGATATTGTGGGGTTGTTAGAAGGAGTGTTT GTCGTATAGAATTATTGGTGATGGCCTGGATGCGGTTTTGTATGAACTGAGAAACTAAAC AAAAGAGTGGCTGCCAGGTGAGTTGAACAGTCTGATTTTCATTGGGGGTCCTTCACAGAT GGGACATGGCTTAGGAGGAATCCCGGGCTGCGGGCATTCCTTGGCCCGGTGGCCAGATTT CCAAAACTTGTAGCAAGCTCCTGGGGGAGGAGGTTCTGGAGGAACCCCTGGCAGCTGCGG TTCAGGCGTTTGGAGTTCTTGTGTTCTGGAGATGTGGCTGGGGTTTGTCTCACGGTGGAG GCAAGGAATTGCAACTCAGAAATACATTGCTACGTGGCTGCCTCTACTCTTATTATTGTA CACCTTGAAGGCGAGGTTAATTAAGTCCTGTTGTGGGGTATGAGGGCCGGAATTTAATTT TTGGAGCTTTATTTAATGTCAGGAGCAGATTGGGTAATAAAATAAAATGCATTTTGAGAA TAAGACGGCATTGTGACCTTTCAGGGTCTAGGGCTGTAAAACATCTCAGGATTGCTGCCA AATGGGCCATGAACTGGGCTGGGTTTTATATTTGATGAAAAAGAGCCTAAACGCTAACTG ATCTGGGAGAGGTCGGATAAAGAAAAAGGAGCATTAACCTTGACTGTGCCTTTAGCTCCA GCCACCTCTTTAAGAGGAAACTGTTGGGCAGATGGAGGAGGGCTAGTCACGGAAAGAAAC TGTAAGCTGGACTGGGTGTGAGGAGGGGAGGTAATAAAAGGATTATAGGGTGGAGGAGCA GAGGCTGAGGAAGAATTGGGACCTAGCTCGGCCTGGTGAGGAGCAGCCTGGGAAGGAGGG GAGAAGTCAGATGGGTTTGTAGAAAAGGAAGATTCAAGACTCAGCAACGCTTGGGGTTGG AACTGAGGGGACAGGCAGGAGGGAAAGAAGGAAGATTTGGGATGAACTGCATTGGGAACA GAGACTAGGGAGGGACCGATGTATAAAAGAATGCCTGAACGTCAGGCACCTCAGACCATT TGCCCATTTTATGACAAGAATTATTTAGATCTTGTAGGATGGAAAAATTGAAAGTGCCAT TTTTTGGCTATTTGGAACCACTGTCTGGTTTGTATTGGGGTCAAGCGGCATTGCAGAAGA AAATAAGACATTTAGGTTTTAGGTCAGGCGAGAGTTGAAGAGGTTTTAAGTTCTTGAGAA CACAGGCTAAGGGAGAGGAAGGAGGAATGGAGGGTGGAAGGTTGCCCATAGTGAAGTAGG CAAGTTTAAAGAGAAGGGTAGAGACACGGAGAGAAGGGGTGGGGGATGCTTATCCCCCAG GAAAGTGGAGAAGGGATGGGAGGTGCTTGCCCCCCAGGAAAATGGAAACGGGGTGGGGGG TGCTTGCCCCTCAGGAAAGTAGAGAAGGGGTAGAGACACGGAGAGAAGGGGTAAGGTGAG CAGCCAAAGCAGGCGTCCCTGCAATTGACTTGCCACCAAGGGATGTGGGTGAATGACCAA GGCAGGTGTCCCCGCGGAGATCAGACACAAATGGAATGTGGGTGAATAATCAGGCAGTCG TCCCCACAATGATTAAACACCAAGGGAAGGCTGCCTTCCCAAGTCCGTGACCGGCGCCAG AGTTTTGGGTCCACGGATAAAATGTGTCTCCTTTGTCTATACCAGAAAATGAAAGGAATT TAAATTAAGAGAAGGGAGAGATTGAAGGATGGTGCCAAGATTGAAAGGAGAAAGAGGTTG AGGGATAGTGAGAGAGGTTGGAGAAGGAGTAAAAGAGGCCACTTACCCAATTTAAAATCA GTGAGATGTTCCTTGGGCTGGTTGGTCTGCGGACCTGAGGTTGTAGGTGGATCTCTTCAG GGAGTGAAGGTGAGGACAGGGGACTGCTGTCCCGAAGGAGTCCCGCTGACCCGGGTCTTC GGCACCAAATGTCTCATGCGTCCGTGTGAAGAGACCACCAAACAGGCTTTGTGTGAGCAA CGAGGCTGTTTATTTCACCTGGGTGCAGGCGGGCTGAGTCCAAAAAGAGAGTCATCAAAG GGTAGTGGGATTATCATTGGTTCTTATAGGTTTTGGGATAGGCGGTGGAGTTAGGAGCAA TGTTCTGTGGGCAGGGGTGGATCTCACAAAGTACATTCTCAAGGGTGGGGAGAATTACAA AGAACCTTTTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTCGCCCAGGCTGGAGTGC AGTGGCTCTTTCTCGGCTCACTGCAAGCTCCGCCTCCCGAGTTCAAGCCATTCTCCTGCC TCAGCCTCCGGAGTAGCTGGGACCACAGGCGCCCGCCACTACGCCCAGCTAATTTTTTTT TGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTTCTGAC CTCGTGATCTGCCCGCCTCGGCCTCCCAAAGAGCTAGGATTACAGGCTTGGGCCACCGTG CCCGGCCTACAAAGAACCTTCTTAAGGGTGGGGGAGATTACAAAGTATATTGATCAGTTA GGGTGGGGCAGAAACAGATCACAATGGTGGAATGTCATCAGCTAAGGCTATTTTCACTTC TTTTGTAGATCTTCAGTTGCTTCAGGCCATTTGAACGTATATGAGCCGGTCGTAGGGGAT ATGATGGCTTAGCTTGGGCTCAGAGGCCTGAAAATCGCCCCCACCAATCACCTGTTTCCC CCAATCTACCCTCCTGAAGGTCACTGACAAAGACTTCATTGTCTCCTAGGAGAGGCTGCC ATATATCCAGGGCTGACGTAATTCCATCTTAATATCAGTTACATTATAAAAATTTACCTC GTGCCTGAGGCCCCAGAGCCCAAGGGTGCAAAGCAGTAATTGGTCAAAGTTCAACTTCCC TCCCACTCTGGGCTCAGGCTGTCCCCTGAGGGCCTGTGTTTTGAGTCTCTTTCCAGAACC TTGGTGTGAACTTAGGTCTTGGCGTCGGGATCCCTTTTCGTCACACTCAGGTGACCTACA GGGAGCTCCGCTCGACACTGCAAGGCTTAGACCAGTTCGGTCCAACAGAGAAAGCAGGCA ACCACCATGTCATTTGAAAACAGTTTCATCGGGATATAATTCGCAACCCATACAGTGAAT CCATTTAAGGTGTGTAAGTCAAAAGTTTTTCGTGTATTACCTTATGTTTATTTATTTATT TATTTATTTATTTATTTATTTTGAGATGGAGTCTCGCTCTGTCCCCCAGTCTGGAATGCA GTGGCACTATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCT CAGCCTCCCCAGTAGTAGCTGGGACAACAGGCGCCCGCCATCACGCTTGGCTAATTTTTT GTATTTTTAGTAGAGACGGGGTTTTACCATGTTAGCCAGGATGGTCTCGATCTCCTGACC TTGGGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGAGC CCAGCCTTTTATTTTATTTTTTTAAGACAAGGTCTTGCTCCATCACCCAGGCTGGGGTTA AGTGGCATGATCACAGCTTGCTGCAGCCTCAAACTTCCAGACTAAAGCAATTCCCCCAAG TAGCTGGGACTACAGGCGCATGCCACCTTGCCCGGCAAATTTTTGTATTTTTAGTAGAGT TGGGATTTTGCCATGTTGCCCAGGCTGGTCTTTTTTTAAAAAAATTATTTATTTATTTAT TTTTGAGATGGAATCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTT ACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCATGCCTCAGCCTCCCGAGCAGCTG GGATTACAGGCATGAGCCACCACACTCGGCTTATTTTTGTATTTTTGGTAGAAACAGGGT TTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCCACCTGCCTCAG CCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCAAACCCGGCTATTATTTATTTATT TATTTTTGAGACACAATCTCCCTCTGTCACCCAGGCTGGAATGCAGTGGTGTCATCTTGG CTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAG CTGGGACTACAGGTGTGCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAAATGG GGTTTCATCATGTTGGCCAGGCTGGTCTTAAATTCCTGACCTCAGGTGATCTGCTCACCT CGGCCTCCCAAAGTGCTGGGACTACAGGTGTGAGCCACTCTGCTCGGCCGGTCAGCTCAT ATATTACCTGCAAAACCCAGTCCCATTGTACCTTTCTCTGGCTGAGTCATGGATTCAAGC CTTGCCTCAGTGACATGGGAAGCAATGATGACCGGCTATGCCTTCTCCCCTGCCTCCAGG GCACTTGTATTTCAGTAGACTGGGGAAGACTTCGGGGATTCCAGGAAAGGTCTTGTCTAA TAGGTAGAAGGAAGTGGACTCTGGGACAAGGTCCCTTTGTTCAAACACCAGCTGTGCTGA TTTTTGCTGTGAGTCACTTGGTCTCAGTTTTCTCATCTGTGAAACAGGAATAATAGCAGC TCCTCTCAGGACTCATGGCCCGGAGCTTTGGTAAGCAGGAGATTGTCATCAATGACCCTC ACTCCTCTCTCCTCTCTTCCCAGATACTCTGACCCATGGATCCCCTGGGTGCAGCCAAGC CACAATGGCCATGGCGCCGCTGTCTGGCCGCACTGCTATTTCAGCTGCTGGTGGCTGTGT GTTTCTTCTCCTACCTGCGTGTGTCCCGAGACGATGCCACTGGATCCCCTAGGGCTCCCA GTGGGTCCTCCCGACAGGACACCACTCCCACCCGCCCCACCCTCCTGATCCTGCTACGGA CATGGCCTTTCCACATCCCTGTGGCTCTGTCCCGCTGTTCAGAGATGGTGCCCGGCACAG CCGACTGCCACATCACTGCCGACCGCAAGGTGTACCCACAGGCAGACATGGTCATCGTGC ACCACTGGGATATCATGTCCAACCCTAAGTCACGCCTCCCACCTTCCCCGAGGCCGCAGG GGCAGCGCTGGATCTGGTTCAACTTGGAGCCACCCCCTAACTGCCAGCACCTGGAAGCCC TGGACAGATACTTCAATCTCACCATGTCCTACCGCAGCGACTCCGACATCTTCACGCCCT ACGGCTGGCTGGAGCCGTGGTCCGGCCAGCCTGCCCACCCACCGCTCAACCTCTCGGCCA AGACCGAGCTGGTGGCCTGGGCGGTGTCCAACTGGAAGCCGGACTCAGCCAGGGTGCGCT ACTACCAGAGCCTGCAGGCTCATCTCAAGGTGGACGTGTACGGACGCTCCCACAAGCCCC TGCCCAAGGGGACCATGATGGAGACGCTGTCCCGGTACAAGTTCTACCTGGCCTTCGAGA ACTCCTTGCACCCCGACTACATCACCGAGAAGCTGTGGAGGAACGCCCTGGAGGCCTGGG CCGTGCCCGTGGTGCTGGGCCCCAGCAGAAGCAACTACGAGAGGTTCCTGCCACCCGACG CCTTCATCCACGTGGACGACTTCCAGAGCCCCAAGGACCTGGCCCGGTACCTGCAGGAGC TGGACAAGGACCACGCCCGCTACCTGAGCTACTTTCGCTGGCGGGAGACGCTGCGGCCTC GCTCCTTCAGCTGGGCACTGGATTTCTGCAAGGCCTGCTGGAAACTGCAGCAGGAATCCA GGTACCAGACGGTGCGCAGCATAGCGGCTTGGTTCACCTGAGAGGCCGGCATGGTGCCTG GGCTGCCGGGAACCTCATCTGCCTGGGGCCTCACCTGCTGGAGTCCTTTGTGGCCAACCC TCTCTCTTACCTGGGACCTCACACGCTGGGCTTCACGGCTGCCAGGAGCCTCTCCCCTCC AGAAGACTTGCCTGCTAGGGACCTCGCCTGCTGGGGACCTCGCCTGTTGGGGACCTCACC TGCTGGGGACCTCACCTGCTGGGGACCTTGGCTGCTGGAGGCTGCACCTACTGAGGATGT CGGCGGTCGGGGACTTTACCTGCTGGGACCTGCTCCCAGAGACCTTGCCACACTGAATCT CACCTGCTGGGGACCTCACCCTGGAGGGCCCTGGGCCCTGGGGAACTGGCTTACTTGGGG CCCCACCCGGGAGTGATGGTTCTGGCTGATTTGTTTGTGATGTTGTTAGCCGCCTGTGAG GGGTGCAGAGAGATCATCACGGCACGGTTTCCAGATGTAATACTGCAAGGAAAAATGATG ACGTGTCTCCTCACTCTAGAGGGGTTGGTCCCATGGGTTAAGAGCTCACCCCAGGTTCTC ACCTCAGGGGTTAAGAGCTCAGAGTTCAGACAGGTCCAAGTTCAAGCCCAGGACCACCAC TTATAGGGTACAGGTGGGATCGACTGTAAATGAGGACTTCTGGAACATTCCAAATATTCT GGGGTTGAGGGAAATTGCTGCTGTCTACAAAATGCCAAGGGTGGACAGGCGCTGTGGCTC ACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTAGGAGGATTGATTGAGGCCAAGAGT TAAAGACCAGCCTGGTCAATATAGCAAGACCACGTCTCTAAATAAAAAATAATAGGCCGG CCAGGCA OMIM ID 111100