Entrez gene ID | | 252969 |
Official gene symbol | | NEIL2 |
Full name | | nei endonuclease VIII-like 2 (E. coli) |
Aliases | | ,FLJ31644,MGC2832,MGC4505,NEH2,NEI2, |
Gene summary | | NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM] |
Location | | Chromosome: 8 Locus: 8p23.1 |
Gene position | | 11627172 - 11644854 Map Viewer |
Gene orientation | | plus |
Gene size | | 17683 bp |
Gene sequence |
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OMIM ID | | 608933 |