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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GABBR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2550
Official gene symbolGABBR1
Full namegamma-aminobutyric acid (GABA) B receptor, 1
Aliases,FLJ92613,GABABR1,GABBR1-3,GB1,GPRC3A,dJ271M21.1.1,dJ271M21.1.2,
Gene summaryGamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p21.31
Gene position29600962 - 29570005  Map Viewer
Gene orientationminus
Gene size30958 bp
Gene sequence
OMIM ID603540