Entrez gene ID | | 25545 |
Official gene symbol | | Sepw1 |
Full name | | selenoprotein W, 1 |
Aliases | | MGC105482,SelW |
Gene summary | | This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein has been shown to function as a glutathione-dependent antioxidant in vivo. Studies in rat suggest that it may play an important role as an antioxidant in the developing brain and embryo. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q21 |
Gene position | | 76249868 - 76254941 Map Viewer |
Gene orientation | | minus |
Gene size | | 5074 bp |
Gene sequence |
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