| Entrez gene ID | | 25777 |
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| Official gene symbol | | SUN2 |
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| Full name | | Sad1 and UNC84 domain containing 2 |
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| Aliases | | ,KIAA0668,MGC133055,MGC133056,UNC84B, |
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| Gene summary | | SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM] |
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| Location | | Chromosome: 22 Locus: 22q13.1 |
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| Gene position | | 39151947 - 39130735 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 21213 bp |
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| Gene sequence |
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| OMIM ID | | 613569 |
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