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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXO7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID25793
Official gene symbolFBXO7
Full nameF-box protein 7
Aliases,DKFZp686B08113,FBX,FBX07,FBX7,PARK15,PKPS,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q12-q13
Gene position32870707 - 32894818  Map Viewer
Gene orientationplus
Gene size24112 bp
Gene sequence
OMIM ID605648