Entrez gene ID | | 25805 |
Official gene symbol | | BAMBI |
Full name | | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) |
Aliases | | ,NMA, |
Gene summary | | This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10p12.3-p11.2 |
Gene position | | 28966424 - 28971868 Map Viewer |
Gene orientation | | plus |
Gene size | | 5445 bp |
Gene sequence |
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OMIM ID | | 604444 |
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