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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BAMBI (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID25805
Official gene symbolBAMBI
Full nameBMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
Aliases,NMA,
Gene summaryThis gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq]
LocationChromosome: 10   Locus: 10p12.3-p11.2
Gene position28966424 - 28971868  Map Viewer
Gene orientationplus
Gene size5445 bp
Gene sequence
OMIM ID604444