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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FBXL2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID25827
Official gene symbolFBXL2
Full nameF-box and leucine-rich repeat protein 2
Aliases,DKFZp564P0622,FBL2,FBL3,
Gene summaryThis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p22.3
Gene position33318934 - 33428757  Map Viewer
Gene orientationplus
Gene size109824 bp
Gene sequence
OMIM ID605652