Entrez gene ID | | 25855 |
Official gene symbol | | BRMS1 |
Full name | | breast cancer metastasis suppressor 1 |
Aliases | | ,DKFZp564A063, |
Gene summary | | This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13-q13.2 |
Gene position | | 66112582 - 66104804 Map Viewer |
Gene orientation | | minus |
Gene size | | 7779 bp |
Gene sequence |
| |
OMIM ID | | 606259 |